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( A ) IB analysis using specific Abs against Pklr and Pkm2 in unfractionated RBCs (whole RBCs) and fractionated RBCs, according to density in F1(density N1.074, corresponding to a young and reticulocyte-enriched fraction) and F2 (density N1.092, corresponding to older RBCs) from WT and 4.2 / mice

Changes in mood or behaviour during any new medication warrant professional assessment

Likely not significantly, but some cardiologists worried theoretically it could stress the heart

Starting Dose (Weeks 1-4): 2 mg Every patient begins at 2 mg once weekly, regardless of target maintenance dose

Glutathione c tc dng chng oxy ha mnh , gip lm sng da, lm chm lo ha v tng cng min dch